Molecular process films and poster-resolution frames, rendered locally in the browser from deposited structural data.
Motion contact sheet · 08 studies
Eight films span seven mechanisms and eight visual languages: the complete leading/lagging replication fork in both cartoon and molecular-surface treatments, processive synthesis, measured primer extension, a surface gate, ligand binding and release, a clamp ratchet, and an authored signal relay. Every film opens as an editable Molstudio scene.
T7 replisome · mechanistic composite
A parental duplex reaches the T-shaped fork, where the leading template routes outside gp4 and the lagging template threads through its central channel. Opposed gp5–thioredoxin polymerases then show continuous leading synthesis beside four-nucleotide T7 priming, lagging-strand loop growth and release, and two emerging daughter duplexes.
T7 replisome · actor-local molecular surfaces
The same asymmetric fork choreography is staged through hydrated molecular surfaces, active-site cutaways, and restrained contact waves. The leading template still routes outside gp4 for continuous synthesis while the lagging template enters its channel for four-nucleotide priming, looped discontinuous synthesis, and release.
DNA synthesis · processive strand growth
Twenty conserved-atom handoffs drive one continuous DNA conveyor through a stable polymerase. The camera holds the active site, then pulls back to reveal a primer extended from seven to 27 retained units.
DNA synthesis · retained chain growth
The complete deposited seven-base primer stays visible while four dATP copies approach, dwell and hand off in place to retained units. Three intervening full-frame helical translocation beats leave an explicit eleven-base primer.
DNA polymerase · hydrated molecular surface
A clipped molecular surface exposes the active-site cleft as the selected domain opens, admits the staged nucleotide, and closes around its deposited pose.
Kinase recognition · ghosted surface + ligand space-fill
Track AQ4 into the EGFR cleft, hold at its deposited 1M17 pose while the contact shell resolves, then release along a second independently editable path.
DNA processing · cartoon silhouette + luminous DNA
A locked profile separates clamp and cargo: close, advance the duplex 3.4 Å, then reopen, repeating in three discrete, independently editable beats.
Kinase communication · cartoon map + residue bands
A contact cue at deposited AQ4 travels through four authored residue bands toward the distal lobe, turning a static structure into a clear explanatory signal map.
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